Resveratrol + exercise training
Resveratrol + exercise training has been studied in 2 papers since 2016: none in people yet, 2 in animals. The research so far is in animals. The newest paper, Feb 10, 2023: “Combination resveratrol with exercise training has anti-aging function only at mature stage SAMP8 mice liver”.
2 papers study it6 findingsUpdated
None of its findings points the other way.
- 2 independent labs in 2 countries
- Funder: National Science Council
- Animals2
What did studies of Resveratrol + exercise training find?
6Studies of Resveratrol + exercise training measured 6 outcomes; the most studied are PI3K–AKT signaling (1 study), collagen (1) and apoptosis (1).
PI3K–AKT signaling
upin mice1
1 study
PI3K–AKT signaling
upin mice1
Resveratrol + exercise training activates PI3K–AKT signaling in mice (p<0.001).
“Combination habitual exercise training and resveratrol intake in the 6-month-old SAMP8 mice liver has significant increases in p-PI3K/PI3K (p<0.001) and p-Akt/Akt (p<0.01) ratios”
Animalsmature SAMP8 miceliver
Preprint
Collagen
downin mice1
1 study
Collagen
downin mice1
Resveratrol + exercise training decreases collagen in mice.
“cross-sections of 6-month-old SAMP8 mice livers observed lower adipocytes, collagen, and apoptosis cells appeared after exercise training, resveratrol intake, and their combination”
Animalsmature SAMP8 miceliver
Preprint
Apoptosis
downin mice1
1 study
Apoptosis
downin mice1
Resveratrol + exercise training decreases apoptosis in mice.
“cross-sections of 6-month-old SAMP8 mice livers observed lower adipocytes, collagen, and apoptosis cells appeared after exercise training, resveratrol intake, and their combination”
Animalsmature SAMP8 miceliver
Preprint
Plasma lactate
downin mice1
1 study
Plasma lactate
downin mice1
Resveratrol + exercise training decreases plasma lactate in mice.
“plasma lactate and ammonia levels of the ET + RES group after acute swimming exercise were significantly lower compared to the OC group”
AnimalsAfter acute swimming exercise, compared with older controlplasma4 weeks
Molecules (Basel, Switzerland)
Endurance swimming time
upin mice1
1 study
Endurance swimming time
upin mice1
Resveratrol + exercise training improves endurance swimming time in mice.
“The endurance swimming test showed that swimming times of the ET and ET+RES groups were significantly longer than those of the OC and RES groups.”
AnimalsCompared with older control and resveratrol alone4 weeks
Molecules (Basel, Switzerland)
Forelimb grip strength
upin mice1
1 study
Forelimb grip strength
upin mice1
Resveratrol + exercise training improves forelimb grip strength in mice (1.3-, 1.2-, and 1.1-fold versus OC, RES, and ET groups, respectively).
“the forelimb grip strength of mice in the ET+RES group was significantly higher than those in the OC, RES, and ET groups”
AnimalsCompared with older control, resveratrol alone, and exercise training alone4 weeks
Molecules (Basel, Switzerland)