MAPK7

1. MAPK7 activates pyroptosis in mice.

   Animalsvia NLRP3 phosphorylation at serine 198cartilage

   Inhibition of ERK5 activity ameliorates osteoarthritis by suppressing NLRP3 inflammasome-mediated chondrocyte pyroptosis · Bone research · 2 Sep 2026

Pyroptosis →

1. MAPK7 increases osteoarthritis in mice.

   Animalsshown by cartilage deletioncartilage

   Inhibition of ERK5 activity ameliorates osteoarthritis by suppressing NLRP3 inflammasome-mediated chondrocyte pyroptosis · Bone research · 2 Sep 2026

Osteoarthritis →