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ES9

Intervention

1 paper2 findings

PubChem

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Health and Medical Research Council and 2 more
  • Animals1

Outcomes

2

Body weight

upin mice1

1 study

  1. ES9 increases body weight in mice.

    “0.03% ES9 which significantly improved glucose tolerance, blood glucose levels, and HbA1c, but increased body weight, liver size and steatosis relative to db/db controls.”

    Animalsin db/db mice0.03% (w/w)4 weeksmales

    Diverse actions of 15 structurally unrelated mitochondrial uncouplers in cells and mice

    Molecular metabolismJul 8, 2025

Blood glucose

downin mice1

1 study

  1. ES9 decreases blood glucose in mice.

    “0.03% ES9 which significantly improved glucose tolerance, blood glucose levels, and HbA1c, but increased body weight, liver size and steatosis relative to db/db controls.”

    Animalsin db/db mice0.03% (w/w)4 weeksmales

    Diverse actions of 15 structurally unrelated mitochondrial uncouplers in cells and mice

    Molecular metabolismJul 8, 2025

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