ERO1A knockdown
Intervention1 paper1 finding
- Animals1
Outcomes
1Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
ERO1A knockdown decreases cellular senescence in human cells.
CellsTGF-β-induceddermal fibroblast
Parthenolide reduces senescence and skin fibrosis in scleroderma models · Aging cell · 30 Sep 2026
Latest
1AnimalsMitochondria
Parthenolide reduces senescence and skin fibrosis in scleroderma models
The compound targets Ero1L to stabilize contacts between mitochondria and the endoplasmic reticulum, mitigating tissue damage in cells and mice.