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Empirical dietary inflammatory pattern

Empirical dietary inflammatory pattern has been studied in 6 papers since 2021: 6 observational studies in people; 4 in the past year. The newest story, Nov 4, 2026: “Healthy-diet blood patterns linked to lower odds of eye disease”.

Intervention

6 papers study it4 findingsUpdated

2 new papers in 30 daysSee all 6 papers on empirical dietary inflammatory pattern

At a glance

The findings reach people, from one lab or study. 2 independent labs in 1 country.

“those in the highest quintile had a higher risk of overall death (hazard ratio (HR) = 1·19, 95 % CI 1·08, 1·32, Ptrend = 0·002)”
Association of dietary inflammatory potential with risk of overall and cause-specific mortalityThe British journal of nutrition2021doi:10.1017/s0007114521002907

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 1 country
  • Humans6

What is empirical dietary inflammatory pattern linked with?

4

Studies link empirical dietary inflammatory pattern with 4 measures, most often transition from normal cognition to cognitive impairment (1 study), cardiovascular disease (1) and cancer (1).

Transition from normal cognition to cognitive impairment

upin humans1HR 1.074

1 study

  1. Empirical dietary inflammatory pattern is associated with transition from normal cognition to cognitive impairment in humans (HR 1.074 per 1-SD higher EDIP, 95% CI 1.014–1.138).

    “The primary hazard ratio (HR) per 1-SD higher EDIP was 1.074 (95% confidence interval [CI], 1.014-1.138; P = 0.014).”

    HumansRestricted primary model assigning EDIP only to the normal-to-impairment transition; without dementia at baselineper 1-SD higher EDIP2014–2022n = 4,997

    Empirical dietary inflammatory pattern and cognitive-state transitions in older US adults: a multistate cohort study

    Frontiers in nutrition

Cardiovascular disease

no changein humans1HR 1.22

1 study

  1. Empirical dietary inflammatory pattern is associated with cardiovascular disease in humans (HR = 1.22, 95% CI 0.98, 1.53).

    “and CVD (HR = 1·22, 95 % CI 0·98, 1·53, Ptrend = 0·211)”

    Humansmedian follow-up of 7.8 yearsn = 40,074

    Association of dietary inflammatory potential with risk of overall and cause-specific mortality

    The British journal of nutrition

More on Cardiovascular disease

Cancer

upin humans1HR 1.41

1 study

  1. Empirical dietary inflammatory pattern is linked with a higher risk of cancer in humans (HR = 1.41, 95% CI 1.14, 1.74).

    “and deaths from cancer (HR = 1·41, 95 % CI 1·14, 1·74, Ptrend = 0·017)”

    Humansmedian follow-up of 7.8 yearsn = 40,074

    Association of dietary inflammatory potential with risk of overall and cause-specific mortality

    The British journal of nutrition

More on Cancer

Overall mortality

upin humans1HR 1.19

1 study

  1. Empirical dietary inflammatory pattern is linked with a higher risk of overall mortality in humans (HR = 1.19, 95% CI 1.08, 1.32).

    “those in the highest quintile had a higher risk of overall death (hazard ratio (HR) = 1·19, 95 % CI 1·08, 1·32, Ptrend = 0·002)”

    Humansmedian follow-up of 7.8 yearsn = 40,074

    Association of dietary inflammatory potential with risk of overall and cause-specific mortality

    The British journal of nutrition

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 1Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 14 papers in 12 months
Investigative Ophthalmology & Visual Science

Healthy-diet blood patterns linked to lower odds of eye disease

Blood signatures of four healthy diets were linked to 12% to 16% lower odds of age-related macular degeneration per standard-deviation increase.Blood signatures of four healthy diets were linked to 12% to 16% lower odds of age-related macular degeneration per standard-deviation increase.

Cross-sectional · 504 peopleEye
Paper

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