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Eldr-targeting gapmer

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab
  • Animals1

Outcomes

2

Cartilage degradation

downin mice1

1 study

  1. Eldr-targeting gapmer decreases cartilage degradation in mice.

    “GapmeR-mediated silencing of ELDR in OA model substantially attenuates chondrocyte senescence and cartilage degradation.”

    Animalsosteoarthritis modelGapmeRcartilage

    A novel transcript of LncRNA ELDR promotes chondrocyte senescence and osteoarthritis progression by tuning chromosomal dynamics

    Research Square10 Jun 2022Preprint

chondrocyte senescence

downin mice1

1 study

  1. Eldr-targeting gapmer decreases chondrocyte senescence in mice.

    “GapmeR-mediated silencing of ELDR in OA model substantially attenuates chondrocyte senescence and cartilage degradation.”

    Animalsosteoarthritis modelGapmeRcartilage

    A novel transcript of LncRNA ELDR promotes chondrocyte senescence and osteoarthritis progression by tuning chromosomal dynamics

    Research Square10 Jun 2022Preprint

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