ELDR
1 paper2 findings
- 1 lab
- Animals1
Effects
2Senescence marker expression
upin human cells1
1 study
Senescence marker expression
upin human cells1
ELDR increases senescence marker expression in human cells.
“Clinically, ELDR knockdown in cartilage explants from OA patients decreased the expression of senescence markers and catabolic mediators.”
Cellsosteoarthritis; shown by ELDR knockdowncartilage explants
Research Square10 Jun 2022Preprint
chondrocyte senescence
upin mice1
1 study
chondrocyte senescence
upin mice1
ELDR induces chondrocyte senescence in mice.
“we show that a novel transcript of long noncoding RNA ELDR is essential for the development of chondrocyte senescence.”
Animalsgenetically engineered mouse modelscartilage
Research Square10 Jun 2022Preprint
Latest
Research Square
A novel transcript of LncRNA ELDR promotes chondrocyte senescence and osteoarthritis progression by tuning chromosomal dynamics
Preprint: experiments in miceOsteoarthritis