DP71L

1. DP71L improves memory in mice.

   “and enhanced synaptic plasticity and memory in healthy mice.”

   Animalshealthy mice

   Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response

   Science (New York, N.Y.)·2 Apr 2026

1. DP71L improves synaptic plasticity in mice.

   “and enhanced synaptic plasticity and memory in healthy mice.”

   Animalshealthy mice

   Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response

   Science (New York, N.Y.)·2 Apr 2026

1. DP71L improves cognitive function in mice.

   “DP71L reversed the cognitive and synaptic deficits across mouse models of Down syndrome, Alzheimer's disease, and aging”

   Animalsmouse models of Down syndrome, Alzheimer's disease, and aging

   Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response

   Science (New York, N.Y.)·2 Apr 2026

1. DP71L inhibits integrated stress response in mice.

   “Furthermore, we characterized DP71L, a viral ortholog of PPP1R15B, which acted as a potent pan-ISR inhibitor.”

   Animals

   Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response

   Science (New York, N.Y.)·2 Apr 2026

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