Dietary restriction + exercise

1. Dietary restriction + exercise decreases lipid peroxidation in mice.

   “Lipid peroxidation and iron accumulation were more effectively attenuated in RG than in WG following HFRV intervention.”

   Animalsobese micered gastrocnemius

   Differential ferroptosis regulation in red and white gastrocnemius under obesity and its Attenuation by exercise and dietary restriction

   Scientific reports·Jul 3, 2025

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1. Dietary restriction + exercise inhibits ferroptosis in mice.

   “HFRV partially reversed ferroptosis in RG by upregulating GPX4, while the effects in WG were limited.”

   Animalsobese micered gastrocnemius

   Differential ferroptosis regulation in red and white gastrocnemius under obesity and its Attenuation by exercise and dietary restriction

   Scientific reports·Jul 3, 2025

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1. Dietary restriction + exercise decreases RUNX2 in mice.

   “RT-qPCR showed a significant decrease in gene expression of both Foxc1 and Runx2 in CAR cells of the DR + ex group compared to CON.”

   AnimalsCAR cells5 weeksfemales

   Dietary restriction plus exercise change gene expression of Cxcl12 abundant reticular cells in female mice

   Journal of bone and mineral metabolism·Apr 1, 2024

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1. Dietary restriction + exercise decreases leukocyte count in mice.

   “The number of leukocytes in the blood was significantly decreased in the DR + ex group compared to the other three groups.”

   Animalswhole blood5 weeksfemales

   Dietary restriction plus exercise change gene expression of Cxcl12 abundant reticular cells in female mice

   Journal of bone and mineral metabolism·Apr 1, 2024

More on Leukocyte count