Cyclic mechanical stretch

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • 1 finding against
  • Funders: National Natural Science Foundation of China and 1 more
  • Humans1

Outcomes

1

Cellular senescence

downin human cells1upin human cells1

1 study
  1. Cyclic mechanical stretch decreases cellular senescence in human cells.

    “physiological stretch attenuated them”

    Cellsat 12% strainlens epithelial cells0.5 Hz

    Regulation of lens epithelial cell senescence by cyclic mechanical stretch: Multi-omics insights into the mechanisms of lens aging

    Experimental eye researchMay 29, 2026

  2. Cyclic mechanical stretch increases cellular senescence in human cells.

    “overloaded stretch increased SA-β-gal staining, p53/p21/p16 expression, and SASP secretion”

    Cellsat 12% strainlens epithelial cells2.5 Hz

    Regulation of lens epithelial cell senescence by cyclic mechanical stretch: Multi-omics insights into the mechanisms of lens aging

    Experimental eye researchMay 29, 2026

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