Polyanhydride nanoparticles + pentablock copolymer micelles + cyclic dinucleotides
1 paper2 findings
- 1 lab in 1 country
- Funders: Iowa State University and 3 more
- Animals1
Outcomes
2Effector memory cells
upin mice1
1 study
Effector memory cells
upin mice1
Polyanhydride nanoparticles + pentablock copolymer micelles + cyclic dinucleotides increase effector memory cells in mice.
“greater effector memory cells in draining lymph nodes compared to an imiquimod-adjuvanted vaccine”
Animalsdraining lymph nodes
Immunity & ageing : I & AJun 21, 2023
Antigen-specific CD4+ T cells
upin mice1
1 study
Antigen-specific CD4+ T cells
upin mice1
Polyanhydride nanoparticles + pentablock copolymer micelles + cyclic dinucleotides increase antigen-specific CD4+ T cells in mice.
“a combination nanovaccine composed of NP, Mi, and CDN administered to aged mice resulted in a greater percentage of antigen-specific CD4+ T cells”
Animalsdraining lymph nodes
Immunity & ageing : I & AJun 21, 2023
Latest
Immunity & Ageing
Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines
Experiments in miceBlood and immune system