Polyanhydride nanoparticles + pentablock copolymer micelles + cyclic dinucleotides

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: Iowa State University and 3 more
  • Animals1

Outcomes

2

Effector memory cells

upin mice1

1 study
  1. Polyanhydride nanoparticles + pentablock copolymer micelles + cyclic dinucleotides increase effector memory cells in mice.

    “greater effector memory cells in draining lymph nodes compared to an imiquimod-adjuvanted vaccine”

    Animalsdraining lymph nodes

    Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines

    Immunity & ageing : I & AJun 21, 2023

More on Effector memory cells

Antigen-specific CD4+ T cells

upin mice1

1 study
  1. Polyanhydride nanoparticles + pentablock copolymer micelles + cyclic dinucleotides increase antigen-specific CD4+ T cells in mice.

    “a combination nanovaccine composed of NP, Mi, and CDN administered to aged mice resulted in a greater percentage of antigen-specific CD4+ T cells”

    Animalsdraining lymph nodes

    Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines

    Immunity & ageing : I & AJun 21, 2023

More on Antigen-specific CD4+ T cells

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