Cyclic dinucleotides

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Iowa State University and 3 more
  • Animals1

Outcomes

1

IFN-α

upin human cells1

1 study
  1. Cyclic dinucleotides increase IFN-α in human cells.

    “Treatment with Mi or CDN resulted in minimal induction of cytokines and chemokine secretion with the exception of increased IFN-α and IL-12p70 by CDN.”

    Cellsperipheral blood mononuclear cells

    Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines

    Immunity & ageing : I & AJun 21, 2023

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