Np

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: National Major Science and Technology Projects of China and 2 more
4 of 4 findings with company ties

Animals1

Outcomes

IFN-γ and TNF-α production by antigen-specific CD4+ and CD8+ T cells

upin mice1

1 study

Np increases IFN-γ and TNF-α production by antigen-specific CD4+ and CD8+ T cells in mice.
Animalsin aged mice
Nanovaccines co-delivering antigen and dual TLR agonists potentiate aged immunity by orchestrating TCR repertoire
Journal of controlled release : official journal of the Controlled Release Society13 Aug 2026

More on IFN-γ and TNF-α production by antigen-specific CD4+ and CD8+ T cells

Myeloid-derived suppressor cells

downin mice1

1 study