CYANIDIN-3-GLUCOSIDE

Intervention

2 papers6 findings

PubChem

  • 2 independent labs in 1 country
  • Funder: National Key Research and Development Program of China
  • Animals1
  • Cells1

Outcomes

6

Intestinal damage

downin mice1

1 study
  1. CYANIDIN-3-GLUCOSIDE decreases intestinal damage in mice.

    “C3G also promotes gut health by decreasing inflammatory responses and intestinal tissue crypt damage”

    Animalsnaturally agingintestine

    Cyanidin-3-glucoside improves cognitive impairment in naturally aging mice by modulating the gut microbiota and activating the ERK/CREB/BDNF pathway

    Food research international (Ottawa, Ont.)25 Feb 2025

Blood-brain barrier damage

downin mice1

1 study
  1. CYANIDIN-3-GLUCOSIDE decreases blood-brain barrier damage in mice.

    “attenuating blood-brain barrier and hippocampal synaptic damage”

    Animalsnaturally agingbrain

    Cyanidin-3-glucoside improves cognitive impairment in naturally aging mice by modulating the gut microbiota and activating the ERK/CREB/BDNF pathway

    Food research international (Ottawa, Ont.)25 Feb 2025

Inflammation

downin mice1

1 study
  1. CYANIDIN-3-GLUCOSIDE decreases inflammation in mice.

    “C3G may exert neuroprotective effects and promote brain health by alleviating brain atrophy and neuroinflammation”

    Animalsnaturally agingbrain

    Cyanidin-3-glucoside improves cognitive impairment in naturally aging mice by modulating the gut microbiota and activating the ERK/CREB/BDNF pathway

    Food research international (Ottawa, Ont.)25 Feb 2025

More on Inflammation

Cognitive function

upin mice1

1 study
  1. CYANIDIN-3-GLUCOSIDE improves cognitive function in mice.

    “C3G has the potential to improve natural aging-induced cognitive impairment”

    Animalsnaturally aging

    Cyanidin-3-glucoside improves cognitive impairment in naturally aging mice by modulating the gut microbiota and activating the ERK/CREB/BDNF pathway

    Food research international (Ottawa, Ont.)25 Feb 2025

NAD+

upin mice1

1 study
  1. CYANIDIN-3-GLUCOSIDE increases NAD+ in mice.

    “C3G also reduced IL-1β, IL-6, IL-17A, TNF-α levels and restored NAD+ and NK cell levels in the animals.”

    Animalsin D-gal-induced acute aging mice

    Downregulation of Sirt6 by CD38 promotes cell senescence and aging

    Aging6 Dec 2022

More on NAD+

SIRT6

upin mice1

1 study
  1. CYANIDIN-3-GLUCOSIDE increases SIRT6 in mice.

    “C3G treatment decreased CD38 expression and increased Sirt6 expression in the tissues.”

    Animalsin myocardial tissues of D-gal-induced acute aging mice

    Downregulation of Sirt6 by CD38 promotes cell senescence and aging

    Aging6 Dec 2022

More on SIRT6

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