Constant illumination

Intervention

4 papers6 findings

  • 2 independent labs in 1 country
  • Animals4

Outcomes

1

Lifespan

downin rats3

3 studies
  1. Constant illumination shortens lifespan in rats.

    “constant exposure or natural lighting involved accelerated aging as evaluated by coefficient of homeostatic stability and survival curves shifting to the left.”

    Animalsconstant illumination or natural lighting in the North-West of Russiamales

    Effect of light regimens and melatonin on homeostasis, life span and spontaneous tumorigenesis in male rats

    Voprosy onkologii1 Jan 2008

  2. Constant illumination shortens lifespan in rats (-13.5% mean lifespan in constant, -25.5% in natural).

    “The mean life span of animals exposed to constant or natural illumination decreased by 13.5 and 25.5%”

    Animalsexposed to constant or natural illuminationfemales

    Effect of Ala-Glu-Asp-Gly peptide on life span and development of spontaneous tumors in female rats exposed to different illumination regimes

    Bulletin of experimental biology and medicine1 Dec 2007

  3. Constant illumination shortens lifespan in rats (shorter mean (13.5%), maximum by 9 months).

    “Constant and North-West lighting involved premature aging, shorter mean (13.5 and 25%) and maximum life span (by 9 and 7 months, respectively)”

    Animalscompared with standard lightingfemales

    Lighting effect on spontaneous tumor development in female rats

    Voprosy onkologii1 Jan 2007

Associations

2

Spontaneous tumors

upin rats2

2 studies
  1. Constant illumination raises the risk of spontaneous tumors in rats.

    “Permanent illumination promoted the development of spontaneous tumors in comparison with the standard photoregimen.”

    Animalsmales

    Geroprotective effect of ala-glu-asp-gly peptide in male rats exposed to different illumination regimens

    Bulletin of experimental biology and medicine1 Apr 2008

  2. Constant illumination raises the risk of spontaneous tumors in rats.

    “and a significant increase in spontaneous tumor development rate as compared with standard lighting.”

    Animalscompared with standard lightingfemales

    Lighting effect on spontaneous tumor development in female rats

    Voprosy onkologii1 Jan 2007

More on Spontaneous tumors

Neoplasm

upin rats1

1 study
  1. Constant illumination raises the risk of neoplasm in rats.

    “Constant illumination was followed by a significantly faster spontaneous tumorigenesis as compared with standard lighting.”

    Animalscompared with standard lightingmales

    Effect of light regimens and melatonin on homeostasis, life span and spontaneous tumorigenesis in male rats

    Voprosy onkologii1 Jan 2008

More on Neoplasm

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