Light deprivation

Intervention

2 papers6 findings

  • 1 lab
  • Animals2

Outcomes

3

Lifespan

upin mice1upin rats1+14% to +21%

2 studies
  1. Light deprivation extends lifespan in rats.

    “Light deprivation resulted in a longer maximum life span and significant (2.1 times) drop in tumor incidence.”

    Animalsfemales

    Lighting effect on spontaneous tumor development in female rats

    Voprosy onkologii1 Jan 2007

  2. Light deprivation extends lifespan in mice (+21%).

    “maximum life span--by 21%.”

    Animalsfemales

    Effect of light deprivation on homeostasis, life span and development of spontaneous tumors in HER-2/neu transgenic mice

    Voprosy onkologii1 Jan 2004

  3. Light deprivation extends lifespan in mice (+13.5%).

    “Mean survival rate among experimental mice was higher by 13.5% than in control (p 0.001).”

    Animalsfemales

    Effect of light deprivation on homeostasis, life span and development of spontaneous tumors in HER-2/neu transgenic mice

    Voprosy onkologii1 Jan 2004

Tumor

upin mice1

1 study
  1. Light deprivation increases tumor in mice (2-fold).

    “number of tumor bearers under 7 months in the study group was twice that in control (p<0.05)”

    Animalsfemales

    Effect of light deprivation on homeostasis, life span and development of spontaneous tumors in HER-2/neu transgenic mice

    Voprosy onkologii1 Jan 2004

More on Tumor

Body mass

downin mice1

1 study
  1. Light deprivation decreases body mass in mice.

    “Light deprivation was followed by inhibited intake of feed, decreased body mass”

    Animalsfemales

    Effect of light deprivation on homeostasis, life span and development of spontaneous tumors in HER-2/neu transgenic mice

    Voprosy onkologii1 Jan 2004

Associations

1

Spontaneous tumors

downin rats1

1 study
  1. Light deprivation lowers the risk of spontaneous tumors in rats (2.1 times drop).

    “Light deprivation resulted in a longer maximum life span and significant (2.1 times) drop in tumor incidence.”

    Animalsfemales

    Lighting effect on spontaneous tumor development in female rats

    Voprosy onkologii1 Jan 2007

More on Spontaneous tumors

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