Connexin 43-enriched small extracellular vesicles

Connexin 43-enriched small extracellular vesicles has been studied in 1 paper since 2022: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Aug 5, 2022: “Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression”.

Intervention

1 paper studies it1 findingUpdated

  • 1 lab in 1 country
  • Funders: EuroNanoMed III and 3 more
  • Cells1

What did studies of Connexin 43-enriched small extracellular vesicles find?

1

Studies of Connexin 43-enriched small extracellular vesicles measured 1 outcome; the most studied are inflammation (1 study).

Inflammation

upin human cells1

1 study
  1. Connexin 43-enriched small extracellular vesicles induce inflammation in human cells.

    “Cx43-sEVs released by OA-derived chondrocytes spread senescence, inflammation and reprogramming factors involved in wound healing failure to neighbouring tissues”

    Cellsreleased by OA-derived chondrocytes

    Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression

    Cell death & disease

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