Conditioned media from TOP2B-DEFICIENT cells

Exposure

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Department of Biotechnology, Ministry of Science and Technology, India and 1 more
  • Cells1

Outcomes

1

Cellular senescence

upin human cells1

1 study
  1. Conditioned media from TOP2B-DEFICIENT cells induce cellular senescence in human cells.

    “conditioned media from TOP2B-deficient cells were given to wild-type HEK 293T cells, which also developed senescence-like phenotypes.”

    Cellstreatment of wild-type HEK 293T cells

    Deletion of TOP2B promoter using CRISPR-Cas9 induces senescence in HEK 293T cells

    Biochemistry and biophysics reports19 May 2026

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