Clo/asp8-pmk-mcs

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 2 countries

Animals1

Outcomes

Bone formation

upin mice1

1 study

Clo/asp8-pmk-mcs increase bone formation in mice.
“reduce osteoclast-related parameters and serum bone resorption markers, and enhance bone formation.”
Animalsovariectomized micecloperastine-loaded Asp8-modified methionine/lysine-based ROS-responsive polyethylene glycol micellesbone
Drug-carrying particles reduced bone loss in mice
Advanced science (Weinheim, Baden-Wurttemberg, Germany)11 Oct 2026

Bone loss

downin mice1

1 study

Clo/asp8-pmk-mcs decrease bone loss in mice.
“In ovariectomized mice, Clo/Asp8-PMK-MCs attenuate ovariectomy-induced bone loss”
Animalsovariectomized micecloperastine-loaded Asp8-modified methionine/lysine-based ROS-responsive polyethylene glycol micellesbone
Drug-carrying particles reduced bone loss in mice
Advanced science (Weinheim, Baden-Wurttemberg, Germany)11 Oct 2026

Latest

1 in 12 months

Advanced ScienceYesterday

Drug-carrying particles reduced bone loss in mice

In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.

Experiments in miceBones and joints

Paper

Clo/asp8-pmk-mcs

Outcomes

Latest

Drug-carrying particles reduced bone loss in mice

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