Ciglitazone
- 1 lab in 1 country
- Funder: Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Animals1
Outcomes
2BCL2
downin rat cells1
1 study
BCL2
downin rat cells1
Ciglitazone decreases BCL2 in rat cells.
“In new CL, ciglitazone decreased mRNA for bcl-2 on proestrus, estrus, and metestrus.”
Cellsin new CL on proestrus, estrus, and metestruscorpus luteum
Reproduction (Cambridge, England)1 Jan 2007
Progesterone
no changein rat cells1
1 study
Progesterone
no changein rat cells1
Ciglitazone has no effect on progesterone in rat cells.
“There was no effect of PPARgamma agonists or the antagonist on luteal progesterone production in vitro, or levels of mRNA for 20alpha-HSD.”
Cellsin vitrocorpora lutea
Reproduction (Cambridge, England)1 Jan 2007
Latest
Reproduction
Potential role for peroxisome proliferator-activated receptor gamma in regulating luteal lifespan in the rat
Experiments in animalsMechanisms