Childhood socioeconomic status

4 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

3 independent labs in 1 country

Funders: National Institute on Aging and 1 more

Humans4

Outcomes

Racial differences in cognitive functioning

downin humans1

1 study

Childhood socioeconomic status decreases racial differences in cognitive functioning in humans.
“childhood socioeconomic conditions and educational attainment greatly attenuated racial differences in cognitive functioning”
Humansin the US and Brazil
SOCIOECONOMIC DETERMINANTS OF RACIAL INEQUALITIES IN COGNITIVE FUNCTIONING AMONG ADULTS 50+ IN THE US AND BRAZIL
GSA 2024 abstract31 Dec 2024

Associations

Strength of the association between DNA methylation age and IQ change

upin humans1

1 study

Childhood socioeconomic status is associated with Strength of the association between DNA methylation age and IQ change in humans.
“The relationship between DNAmAge and ΔIQ was moderated by childhood SES, with a stronger effect observed among twins from low SES backgrounds.”
HumansTwins from low socioeconomic status backgroundsChildhood to midlifen = 287
Second generation DNA methylation age predicts cognitive change in midlife: the moderating role of childhood socioeconomic status
Aging23 Jul 2025

DunedinPACE

upin humans1

1 study

Childhood socioeconomic status is associated with DunedinPACE in humans (β = 0.05, 95% CI: 0.02, 0.08).
“and DunedinPACE (β = 0.05, 95% CI: 0.02, 0.08).”
Humanslow childhood SES compared with high childhood SESperipheral bloodn = 359
Impact of socioeconomic conditions across the life course on epigenetic age acceleration: evidence from a longitudinal cohort
The journals of gerontology. Series A, Biological sciences and medical sciences11 Jul 2025