Cartilage polypeptide complex

Cartilage polypeptide complex has been studied in 2 papers since 2023: none in people yet, 2 in cells. No study of it in people or animals has been published yet. The newest paper, Jan 1, 2023: “The influence of peptides on the chondrogenic differentiation of human mesenchymal stem cells during replicative aging”.

Intervention

2 papers study it2 findingsUpdated

More peptides

None of its findings points the other way.

  • 1 lab in 1 country
  • Cells2

What did studies of Cartilage polypeptide complex find?

2

Studies of Cartilage polypeptide complex measured 2 outcomes; the most studied are stem cell differentiation (1 study) and senescence-associated secretory phenotype (SASP) (1).

Stem cell differentiation

upin human cells1

1 study
  1. Cartilage polypeptide complex induces stem cell differentiation in human cells.

    “CPC has the same effect in the concentration 2000 ng/ml.”

    Cellsduring replicative aging2000 ng/ml

    The influence of peptides on the chondrogenic differentiation of human mesenchymal stem cells during replicative aging

    Advances in gerontology = Uspekhi gerontologii

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Senescence-associated secretory phenotype (SASP)

downin cells1

1 study
  1. Cartilage polypeptide complex inhibits senescence-associated secretory phenotype (SASP) in cells.

    “Peptides AED and CPC normalize the synthesis of molecules that form SASP of chondrocytes.”

    Cells

    Peptides prevent the forming of secretory phenotype of chondrocytes associated with the aging

    Advances in gerontology = Uspekhi gerontologii

More on Senescence-associated secretory phenotype (SASP)

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