1 paper4 findings
Subjective sleep quality
no changein humans1
Cannabis sativa has no effect on subjective sleep quality in humans.
Humans35 yearsn = 1,128
Cannabis use linked to poorer objective sleep in middle age
JAMA network open1 Oct 2026
Low sleep percentage
upin humans1OR 1.1
Cannabis sativa is associated with low sleep percentage in humans (OR, 1.10; 95% CI, 1.06-1.14).
Humanscumulative cannabis exposure per cannabis-year35 yearsn = 891
Cannabis use linked to poorer objective sleep in middle age
JAMA network open1 Oct 2026
High sleep fragmentation
upin humans1OR 1.04
Cannabis sativa is associated with high sleep fragmentation in humans (OR, 1.04; 95% CI, 1.01-1.08).
Humanscumulative cannabis exposure per cannabis-year35 yearsn = 891
Cannabis use linked to poorer objective sleep in middle age
JAMA network open1 Oct 2026
Prolonged wakefulness after sleep onset
upin humans1OR 1.21
Cannabis sativa is associated with prolonged wakefulness after sleep onset in humans (OR, 1.21; 95% CI, 1.10-1.34).
Humanscumulative cannabis exposure per cannabis-year35 yearsn = 891
Cannabis use linked to poorer objective sleep in middle age
JAMA network open1 Oct 2026
In a 35-year cohort of adults around age 61, each year of cumulative cannabis use was linked to higher odds of prolonged nighttime wakefulness.In a 35-year cohort of adults around age 61, each year of cumulative cannabis use was linked to higher odds of prolonged nighttime wakefulness.