Cannabidiol

  • 1 lab in 1 country
  • Animals2

Outcomes

3

Inflammation

upin mice1

1 study
  1. Cannabidiol increases inflammation in mice.

    “The CBD group showed increased [ 11 C]PK11195 uptake in the WB ( p <0.0001) and hippocampus ( p <0.0001) at 8 months of age.”

    Animalsin Ts65Dn trisomic micebrain

    Exploring the synergistic effects of physical exercise and cannabidiol treatment in a mouse model of Down syndrome using positron emission tomography

    AAIC 2025 abstract25 Dec 2025

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Cognitive function

no changein mice1

1 study
  1. Cannabidiol has no effect on cognitive function in mice.

    “No significant differences were observed in the behavioral assessments.”

    Animalsin 3xTg-AD mice20 mg/kg30 days

    Evaluation of the effect of cannabidiol treatment on [ ¹⁸ F]FDG and [ ¹¹ C]PK11195 uptake in an animal model for Alzheimer's disease

    AAIC 2025 abstract24 Dec 2025

18F-FDG uptake

upin mice1

1 study
  1. Cannabidiol increases 18F-FDG uptake in mice.

    “CBD‐females had higher [ 18 F]FDG uptake than vehicle‐females at 18 months ( p = 0.024).”

    Animalsin 3xTg-AD micewhole brain20 mg/kg30 daysfemales

    Evaluation of the effect of cannabidiol treatment on [ ¹⁸ F]FDG and [ ¹¹ C]PK11195 uptake in an animal model for Alzheimer's disease

    AAIC 2025 abstract24 Dec 2025

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