Body weight

1. Body weight showed no clear effect on post-operative cognitive dysfunction in humans (body weight analysed continuously) (RR 0.99 per kg (95% CI 0.89–1.09)).

   “relative risk 0.99 per kg; 95% confidence interval 0.89, 1.09; p = 0.83”

   Reviewbody weight analysed continuouslyper kg

   Obesity and post-operative cognitive dysfunction: a systematic review and meta-analysis

   Diabetes/metabolism research and reviews·Feb 19, 2016

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1. Body weight is associated with platelet count in dogs.

   “Platelet count had a negative association with body weight.”

   Animalsn = 47

   The companion dog as a model for inflammaging: a cross-sectional pilot study

   GeroScience·Jun 1, 2024

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1. Body weight is associated with GDF-15 in the overweight/obese group (adj. R2 = 0.398; β = 0.11).

   “we found positive associations (all p ≤ 0.020) of body weight (adj. R2 = 0.398; β = 0.11)”

   Humansin the overweight/obese groupn = 514

   Growth differentiating factor-15 and adiposity in young adults: The African-PREDICT study

   International journal of obesity (2005)·Mar 22, 2021

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1. Body weight is associated with plasma neurofilament light chain in dogs (lower body weight associated with higher pNfL) (P < 0.001).

   “decreased body weight (P < 0.001)”

   Animalslower body weight associated with higher pNfLn = 55

   Neurofilament light plasma concentration positively associates with age and negatively associates with weight and height in the dog

   Neuroscience letters·Dec 24, 2020

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1. Body weight is associated with epigenetic age in mice.

   “Both higher BW and the HFD were associated with accelerated epigenetic aging.”

   Animalsliverfemalesn = 70

   Body weight and high-fat diet are associated with epigenetic aging in female members of the BXD murine family

   Aging cell·Aug 12, 2020

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1. Body weight is associated with sphingomyelin in dogs (independent of age).

   “sphingomyelins were significantly higher in large, short-lived dogs, independent of age”

   Animalsindependent of age

   Alterations of Lipid Metabolism With Age and Weight in Companion Dogs

   The journals of gerontology. Series A, Biological sciences and medical sciences·Aug 5, 2020

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1. Body weight is associated with tryptophan pathway metabolites in dogs after controlling for location.

   “tryptophan metabolism emerged as significantly associated with weight of the dogs, with small dogs having significantly higher levels of tryptophan pathway metabolites”

   Animalsafter controlling for location

   Tryptophan metabolism is differently regulated between large and small dogs

   GeroScience·Nov 29, 2019

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1. Body weight raises the risk of mortality in dogs (body weight measured at 10 years of age) (HR = 1.19 per additional kg, P = 0.004).

   “for each additional kg of BW at 10 years, dogs had a 19% higher hazard (HR = 1.19, P = 0.004)”

   Animalsbody weight measured at 10 years of agen = 39

   Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs

   Acta veterinaria Scandinavica·Sep 9, 2019