Antiretroviral drugs
Antiretroviral drugs has been studied in 2 papers since 2019: 1 observational study in people, 1 review; 1 in the past year. The newest paper, Aug 26, 2026: “The burden of Lipoprotein(a) [Lp(a)] in Africa: A systematic review”.
2 papers study it1 findingUpdated
See all 2 papers on antiretroviral drugs
At a glance
The findings reach cells, none yet in people. 1 lab in 1 country.
Cells: a single group. Worms or flies, mice and humans: nothing yet.
- 1 lab in 1 country
- Funders: American Heart Association and others
- Humans1
What did studies of antiretroviral drugs find?
1Studies of antiretroviral drugs measured 1 outcome; the most studied are cellular senescence (1 study).
Cellular senescence
upin human cells1
1 study
Cellular senescence
upin human cells1
Antiretroviral drugs increase cellular senescence in cultured macrophages.
“Many of the antiretroviral drugs individually activated p90RSK, which simultaneously triggered all components of the macrophage senescent phenotype.”
Cellsin cultured macrophagesmacrophage
Circulation
Latest
1 paper in 12 monthsPLOS One
The burden of Lipoprotein(a) [Lp(a)] in Africa: A systematic review
Systematic review of observational studiesPopulations
Circulation
Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals
Cross-sectional study in peopleMAPK/ERK signaling