Anti-müllerian hormone

1. Anti-müllerian hormone prevents follicular depletion.

   “modulating the PI3K/AKT/FOXO3a pathway to help maintain primordial follicle dormancy and prevent premature depletion of the ovarian pool”

   Reviewin folliculogenesis

   The role of anti-Müllerian hormone as a therapeutic agent to preserve the ovarian follicle pool during chemotherapy

   Journal of assisted reproduction and genetics·20 Jun 2026

1. Anti-müllerian hormone protects against chemotherapy-induced gonadotoxicity.

   “AMH can protect the ovarian follicle pool during chemotherapy treatments.”

   Reviewduring chemotherapy treatments

   The role of anti-Müllerian hormone as a therapeutic agent to preserve the ovarian follicle pool during chemotherapy

   Journal of assisted reproduction and genetics·20 Jun 2026

More on Chemotherapy-induced gonadotoxicity

1. Anti-müllerian hormone protects against primordial follicles in mice.

   “We found significantly more primordial follicles in MIS-treated animals than in controls.”

   Animalsduring chemotherapy with carboplatin, doxorubicin, or cyclophosphamidefemales

   AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy

   Proceedings of the National Academy of Sciences of the United States of America·30 Jan 2017

1. Anti-müllerian hormone decreases fertility in mice.

   “exhibited complete and permanent contraception for their entire reproductive lifespan”

   Animalspaired with male breedersfemales

   AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy

   Proceedings of the National Academy of Sciences of the United States of America·30 Jan 2017

1. Anti-müllerian hormone inhibits folliculogenesis in mice.

   “resulted in a complete arrest of folliculogenesis in mice”

   Animalsin female micefemales

   AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy

   Proceedings of the National Academy of Sciences of the United States of America·30 Jan 2017