Anti-icam1-mno2@zif8@tsa

1. Anti-icam1-mno2@zif8@tsa improves oxygenation in mice.

   “restored alveolar structure, boosted oxygenation”

   Animalsin CLP-induced septic mice

   A multifunctional ICAM1-directed MnO₂@ZIF8 nanoplatform with Tanshinone IIA synergistically reverses senescence and restores alveolar regeneration in septic lung injury

   Journal of nanobiotechnology·18 Apr 2026

1. Anti-icam1-mno2@zif8@tsa decreases oxidative stress and ROS signalling in mice.

   “efficiently scavenged reactive oxygen species (ROS)”

   Animalsin CLP-induced septic mice

   A multifunctional ICAM1-directed MnO₂@ZIF8 nanoplatform with Tanshinone IIA synergistically reverses senescence and restores alveolar regeneration in septic lung injury

   Journal of nanobiotechnology·18 Apr 2026

More on Oxidative stress and ROS signalling

1. Anti-icam1-mno2@zif8@tsa decreases cellular senescence in mice.

   “suppresses senescence-related transcriptional signatures”

   Animalsin CLP-induced septic mice

   A multifunctional ICAM1-directed MnO₂@ZIF8 nanoplatform with Tanshinone IIA synergistically reverses senescence and restores alveolar regeneration in septic lung injury

   Journal of nanobiotechnology·18 Apr 2026

More on Cellular senescence

1. Anti-icam1-mno2@zif8@tsa improves survival in mice.

   “markedly increased survival in CLP-induced septic mice”

   Animalsin CLP-induced septic mice

   A multifunctional ICAM1-directed MnO₂@ZIF8 nanoplatform with Tanshinone IIA synergistically reverses senescence and restores alveolar regeneration in septic lung injury

   Journal of nanobiotechnology·18 Apr 2026