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Anti-activin receptor type ii antibody

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 4 countries
  • Funders: American Heart Association and others
  • 1 of 1 finding with company ties
  • Animals1

Outcomes

1

Cardiac function

upin mice1

1 study

  1. Anti-activin receptor type ii antibody improves cardiac function in mice.

    “inhibiting activin A signaling in the early postpartum period with a monoclonal antibody to the activin type II receptor improved heart function”

    Animalsin a murine model of PPCM induced by cardiomyocyte-specific Ppargc1a deletionearly postpartum periodfemales

    Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human

    Science translational medicine17 Apr 2024

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