Activin A

Biomarker1 paper1 finding

  • Human trial1

Interventions

1

SGLT2 inhibitors

downin humans1Very low certainty

1 study
  1. SGLT2 inhibitors decrease activin A in humans.

    Human trialischemic HFrEF with high echocardiographic probability of PHn = 74

    Sodium-glucose cotransporter 2 inhibitors are associated with reduced circulating activin A and modulation of BMP/activin signaling in ischemic cardiomyopathy with high echocardiographic probability of pulmonary hypertension · GeroScience · 31 Aug 2026

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International Journal of Molecular SciencesHumans

Activin A is linked to muscle stem cell shifts in human ageing

Transcriptomic profiling of human skeletal muscle paired with cell experiments identified inflammatory macrophages and Activin A signaling as…Transcriptomic profiling of human skeletal muscle paired with cell experiments identified inflammatory macrophages and Activin A signaling as candidate regulators of altered muscle stem cells.