Andrographolide
- 1 lab in 1 country
- Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 1 more
- Animals1
Outcomes
4Phagocytic capacity
upin mouse cells1
1 study
Phagocytic capacity
upin mouse cells1
Andrographolide increases phagocytic capacity in mouse cells.
“AP significantly alleviated senescence in BV2 microglia while enhancing their phagocytic capacity.”
Cellslow-density lipoprotein-induced senescenceBV2 microglia
iScience20 May 2026
Cellular senescence
downin mouse cells1
1 study
Cellular senescence
downin mouse cells1
Andrographolide decreases cellular senescence in mouse cells.
“AP significantly alleviated senescence in BV2 microglia while enhancing their phagocytic capacity.”
Cellslow-density lipoprotein-induced senescenceBV2 microglia
iScience20 May 2026
Amyloid-β plaque accumulation
downin mice1
1 study
Amyloid-β plaque accumulation
downin mice1
Andrographolide decreases amyloid-β plaque accumulation in mice.
“AP treatment improved cognition performance and reduced amyloid-β (Aβ) plaque accumulation in 5×FAD transgenic mice of both sexes”
Animals5×FAD transgenic mice
iScience20 May 2026
Cognitive function
upin mice1
1 study
Cognitive function
upin mice1
Andrographolide improves cognitive function in mice.
“AP treatment improved cognition performance and reduced amyloid-β (Aβ) plaque accumulation in 5×FAD transgenic mice of both sexes”
Animals5×FAD transgenic mice
iScience20 May 2026
Latest
1 in 12 monthsToxicology and Applied Pharmacology
Molecular mechanisms of andrographolide-induced kidney injury and senescence via SIRT3 inhibition
Experiments in animalsMechanisms
Biochemical Pharmacology
Andrographolide prevents renal fibrosis via decelerating lipotoxicity-mediated premature senescence of tubular epithelial cells
Experiments in animalsInterventions