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4egi-1

Intervention

2 papers1 finding

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Fondation pour la Recherche Médicale and 2 more
  • Animals2

Outcomes

1

GPLD1

upin mice1

1 study

  1. 4egi-1 increases GPLD1 in mice.

    “4EGI-1, which enhances CIT, increased GPLD1 protein without changes in GPLD1 mRNA in cultured fibroblasts and mice.”

    Animalsfibroblasts

    Cap-independent translation of GPLD1 enhances markers of brain health in long-lived mutant and drug-treated mice

    Aging cell5 Aug 2022

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