DCX
Biomarker1 paper1 finding
- Animals1
Interventions
1AAV-IGF1
no changein rats1Very low certainty
1 study
AAV-IGF1
no changein rats1Very low certainty
AAV-IGF1 has no effect on DCX in rats.
“However, molecular analyses of DCX expression did not reveal significant changes, and IBA‐1 marker have yet to be analysed.”
Animalsaged ratsAAV-gfaABC1D-IGF1-TdTomatohippocampus52 daysfemales
Modulation of hippocampal astrocytes in aged rats through insulin‐growth factor 1 gene therapy · AAIC 2025 abstract · 23 Dec 2025