3-iodothyronamine

3-iodothyronamine decreases Aβ neurotoxicity.

“T1AM stimulates trace amine-associated receptor 1 (TAAR1), promoting ERK1/2 phosphorylation, triggering autophagy through mTOR inhibition, and diminishing Aβ neurotoxicity in preclinical models”

Reviewin preclinical models

Thyronines and thyronamines: dual modulators of synaptic plasticity, cognitive decline, and geriatric depression in the aging brain

Behavioural brain research·27 May 2026