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1d11

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Bundesministerium für Bildung und Forschung and 4 more
  • Animals1

Outcomes

1

Osteoporosis

downin mice1

1 study

  1. 1d11 decreases osteoporosis in mice.

    “Treatment of GorabPrx1 conditional knockouts with the TGF-β neutralizing antibody 1D11 rescued the trabecular bone loss”

    Animalsin GorabPrx1 conditional knockout mice

    Targeting TGF-β signaling, oxidative stress, and cellular senescence rescues osteoporosis in gerodermia osteodysplastica

    Aging cell

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