upd1

1 paper1 finding

NCBI Gene Taxon

1 lab in 1 country

Model organisms1

Effects

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Metabolic syndrome

mediatesin flies1

1 study

upd1 mediates metabolic syndrome in flies.
“induces OIS in imaginal disc epithelium and systemically triggers host larval MetS via the conserved cytokine Upd1/IL6.”
Model organismsRas G12V-induced epithelial senescence; supported by genetic suppression of upd1
Ras G12V Oncogene-Induced Epithelial Senescence and Its Relay Promotes Host Metabolic Syndrome in Drosophila
bioRxiv (Cold Spring Harbor Laboratory)17 Mar 2026Preprint

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bioRxiv17 Mar

Ras G12V Oncogene-Induced Epithelial Senescence and Its Relay Promotes Host Metabolic Syndrome in Drosophila

Preprint: experiments in fliesMetabolic syndrome