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SIAT9

Gene

1 paper1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 1 more
  • Animals1

Effects

1

Lifespan

downin mice1

1 study

  1. SIAT9 shortens lifespan in mice.

    “Genetic deletion of Siat9 (GM3 synthetase) or Nr1h2 [liver X receptor (LXR)beta] shortened the life of the npc1(-/-) animals.”

    Animalsin npc1(-/-) mice

    Genetic variations and treatments that affect the lifespan of the NPC1 mouse

    Journal of lipid research12 Dec 2007

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