Rel

4 papers2 findings

NCBI Gene Taxon

2 independent labs in 1 country

Funders: National Key Research and Development Program of China and 5 more

Model organisms4

Effects

1

bmm

mediatesin flies1

1 study

Rel mediates bmm in flies.
“Relish, the conserved regulator of IMD signaling pathway, acts as the downstream target of BubR1 to control the expression level of Bmm”
Model organismsfasting
BubR1 controls starvation-induced lipolysis via IMD signaling pathway in Drosophila
Aging8 Feb 2024

Upstream

1

BNIP3

downin flies1

1 study

BNIP3 inhibits Rel in flies.
“BNIP3 inhibited ROS-mediated activation of Relish, thereby reducing expression of antimicrobial peptide (AMP) genes.”
Model organismsmuscle
BNIP3-Dependent Mitophagy Non-Autonomously Regulates Systemic Aging via NF-κB Suppression in Drosophila
Aging cell1 May 2026

Latest

3 in 12 months

PNAS8 Jul

Dopamine-driven mitochondrial reverse electron transport in immune cells mediates gut-brain ROS signaling during sleep deprivation

Experiments in fliesImmune response

Frontiers in Aging Neuroscience30 Jun

High-saturated-fat diet drives female-biased neurodegeneration in Drosophila via oxidative stress and impaired autophagic flux

Experiments in fliesAutophagy

Aging Cell14 May

BNIP3-Dependent Mitophagy Non-Autonomously Regulates Systemic Aging via NF-κB Suppression in Drosophila

Experiments in fliesMitophagy

Aging9 Feb

BubR1 controls starvation-induced lipolysis via IMD signaling pathway in Drosophila

Experiments in fliesMechanisms