AgingResearch.NewsJoin free

RASGRF1

Gene

4 papers3 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: European Commission and 2 more
  • Animals2

Effects

2

IGF-1

upin mice1downin mice1

2 studies

  1. RASGRF1 increases IGF-1 in mice.

    “IGF-I levels were lower in RasGrf1(-/-) than in controls.”

    Animalsshown by knockout

    RasGrf1 deficiency delays aging in mice

    Aging1 Mar 2011

  2. RASGRF1 decreases IGF-1 in mice.

    “Rasgrf1 mutants are known to have low growth hormone and IGF-1 levels”

    ReviewRasgrf1 mutants

    Paternal genome effects on aging: evidence for a role of Rasgrf1 in longevity determination?

    Mechanisms of ageing and development21 Dec 2010

More on IGF-1

Growth hormone

downin mice1

1 study

  1. RASGRF1 decreases growth hormone in mice.

    “Rasgrf1 mutants are known to have low growth hormone and IGF-1 levels”

    ReviewRasgrf1 mutants

    Paternal genome effects on aging: evidence for a role of Rasgrf1 in longevity determination?

    Mechanisms of ageing and development21 Dec 2010

More on Growth hormone

Latest

Related