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PYCR1

Gene

2 papers3 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 3 countries
  • Funders: Deutsche Forschungsgemeinschaft and 2 more
  • 3 of 3 findings with company ties
  • Humans1
  • Cells1

Associations

3

Chronological age

downin humans1

1 study

  1. Chronological age is associated with PYCR1 in humans.

    “the levels of PYCR1 in the dermis, but not the epidermis, significantly decreased with age.”

    Humansdermis

    PYCR1 Levels Track with Premature and Chronological Skin Aging

    medRxiv28 May 2023Preprint

Proliferative capacity

upin human cells1

1 study

  1. PYCR1 is associated with proliferative capacity in human cells.

    “In both instances, PYCR1 levels dropped and correlated with the loss of proliferative capacity.”

    Cellsinduced or replicative senescencecutaneous fibroblast

    PYCR1 Levels Track with Premature and Chronological Skin Aging

    medRxiv28 May 2023Preprint

Cellular senescence

downin human cells1

1 study

  1. Cellular senescence is associated with PYCR1 in human cells.

    “In both instances, PYCR1 levels dropped and correlated with the loss of proliferative capacity.”

    Cellsinduced or replicative senescencecutaneous fibroblast

    PYCR1 Levels Track with Premature and Chronological Skin Aging

    medRxiv28 May 2023Preprint

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