PLXNB1

PLXNB1 increases ast10 transcriptional signature in mice.

“Genetic ablation of the receptor PLXNB1 , a top‐ranked candidate, reduced the Ast10 transcriptional signature in astrocytes in in vivo and in vitro model systems”

Animalsbrain

Cell‐cell signaling drives a pathologic astrocyte state contributing to cognitive decline in Alzheimer's Disease

AAIC 2025 abstract·23 Dec 2025