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PIR-4913

There is 1 paper on PIR-4913 in aging research: none in people yet, 1 in animals. The newest story, Oct 28, 2026: “Blood-flow pauses reduced injury in aged animal hearts”.

Gene

1 paper studies it1 finding

1 new paper in 30 daysSee all 1

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Animals1

Effects

1

Mitochondrial ATP production

downin animals1

1 study

  1. PIR-4913 decreases mitochondrial ATP production (shown by piR-4913 silencing following ischemia/reperfusion injury).

    “Silencing piR-4913 confers cardioprotection by limiting infarct size, enhancing ATP production, and reducing oxidative stress.”

    Animalsshown by piR-4913 silencing following ischemia/reperfusion injuryheart

    Blood-flow pauses reduced injury in aged animal hearts

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months
Advanced Science

Blood-flow pauses reduced injury in aged animal hearts

Experiments in aged animal hearts linked the benefit to suppression of a small RNA involved in excessive splitting of mitochondria, the cell’s energy-producing…Experiments in aged animal hearts linked the benefit to suppression of a small RNA involved in excessive splitting of mitochondria, the cell’s energy-producing structures.

Rat studyInterventions
Paper

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