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Nucb1

Gene

1 paper1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Kyungpook National University
  • Model organisms1

Effects

1

Insulin/IGF-1 signalling

upin flies1

1 study

  1. Nucb1 activates insulin/IGF-1 signalling in flies.

    “the protein level of phosphorylated AKT, a downstream component of insulin signaling, were decreased in NUCB1 knockdown flies”

    Model organismsshown by knockdown

    NUCB1 is required for proper insulin signaling to control longevity in Drosophila

    Geriatrics & gerontology international20 Mar 2024

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