mcu-1

1. mcu-1 is required for mitochondrial reactive oxygen species in worms.

   Model organismsin PDR-1 deficiencybody-wall muscle

   Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle · Antioxidants (Basel, Switzerland) · 21 Aug 2026

Mitochondrial reactive oxygen species →

1. mcu-1 has no effect on lifespan in worms.

   Model organismsComplex I mutants

   InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevity · Nature communications · 13 Aug 2026