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LXN

Gene

1 paper1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Department of Education, Heilongjiang Province
  • Animals1

Effects

1

Calcium oxalate crystal deposition

upin rats1

1 study

  1. LXN increases calcium oxalate crystal deposition in rats.

    “silencing renal LXN reduced RTEC senescence and M1-like phenotype macrophage polarization and consequently decreased intrarenal CaOx crystal deposition in a rat kidney stone model.”

    Animalsin a rat kidney stone model

    Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage polarization

    Frontiers in immunology2 Oct 2025

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