There are 5 papers on LPCAT3 in aging research: 3 observational studies in people, 1 in animals, 1 in cells.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Innovative Research Team of High-level Local University in Shanghai and 3 more
- Humans3
- Animals1
- Cells1
Effects
2Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
LPCAT3 prevents cellular senescence in human cells (knockdown of LPCAT3).
“Additionally, LPCAT3 knockdown slowed cell cycle progression and accelerated hESCs senescence.”
Cellsknockdown of LPCAT3endometrial stromal cells
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Decidualization
is required forin human cells1
1 study
Decidualization
is required forin human cells1
LPCAT3 is required for decidualization in human cells (knockdown of LPCAT3).
“The knockdown of LPCAT3 in hESCs led to a decrease in the expression of decidual markers and a halt in the characteristic epithelioid-like morphological changes indicative of decidualization.”
Cellsknockdown of LPCAT3endometrial stromal cells
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Latest
1 paper in 12 monthsGeroScience
Genome-wide association study and pathway analysis of healthy aging in Super Seniors
Case-control study in peopleMechanisms
Medicine and Science in Sports and Exercise
Role of LPC 18:1 in the Lipid Metabolic Response to Combined Vitamin D and Resistance Exercise for Protecting Diabetic Skeletal Muscle Function
Study in peopleVitamin D
bioRxiv
Identification of lipid senolytics targeting senescent cells through ferroptosis induction
Preprint: experiments in miceInterventions