KYAT1

1. Caloric restriction increases KYAT1 in silico.

   “Three enzymes that convert kynurenine to kynurenic acid in skeletal muscle, Kyat1, Kyat3 and Got2/Kyat4, are known to increase with endurance exercise and all three increased significantly with CR in aged skeletal muscle.”

   In silicoin aged miceskeletal muscle

   Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle

   Biochimie·20 Nov 2025

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