Psychiatry and Clinical Psychopharmacology
Schizophrenia Multitarget Therapy: Rapamycin Coordinates PI3K-AKT/mTOR Signaling with Cytokine Networks
Computational studyPI3K–AKT signaling
Papers on IL6
21 papers3 new in 30 days
Sunday, November 1
Saturday, October 31
Frontiers in Immunology
Inflammatory Target Engagement and Cardiovascular Protection: A Systematic Review and Meta-Regression of Randomized Immunomodulatory Trials
Accepted, not yet published: meta-analysis of randomized trialsAtherosclerotic cardiovascular disease
Friday, October 30
Frontiers in Immunology
TNF Inhibitor Therapy is associated with an Increase in Absolute Lymphocyte Count that is in turn Associated with Lower Mortality Across the Spectrum of Immune Mediated Inflammatory Diseases
Accepted, not yet published: cohort study of 31,416 peopleJak inhibitors
Thursday, May 7
bioRxiv
Characterization of Cellular Senescence in Primary Human Astrocytes
Preprint: experiments in human cellsCellular senescence
Friday, March 6
Research Square
A plasma proteomic signature of cancer-related sarcopenia implicates the IGFBP axis in muscle dysfunction
Preprint: cohort study in peopleBiomarkers
Advanced Science
Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation
Experiments in animalsInterventions
Tuesday, March 3
Clinical Medicine
The role of the genetic factor in the development of sarcopenia
Cross-sectional study of 67 peopleMuscle
Monday, March 2
Global Heart
Association of Disease-Modifying Antirheumatic Drugs (DMARDs) with Cardiovascular Diseases: Evidence from a Drug Target Mendelian Randomization Study
Mendelian randomization in peopleMechanisms
Friday, February 27
Saturday, February 21
Current Opinion in Biotechnology
Muscle-immune metabolic crosstalk: shared pathways in cachexia and exercise
ReviewMuscle
Thursday, February 19
Scientific Reports
Evaluation of the anti-inflammatory potential of atorvastatin targeting TNF-α, IL-6, and IL-1β using integrated in vitro and in silico approaches
Experiments in mouse cellsAtorvastatin
Wednesday, February 11
Research Square
GLP-1/GLP-1R-mediated glycolytic reprogramming drives AP neuronal hyperactivity in NMOSD
Preprint: experiments in miceGlycolysis
Wednesday, January 7
bioRxiv
Identification of senescence-associated drivers of tumour growth and progression using a novel microarray platform
Preprint: experiments in animalsCellular senescence
Monday, December 8
Friday, August 15
Scientific Reports
GRSF1 loss in THP-1 macrophages promotes senescence-associated transcription in neighboring fibroblasts
Experiments in human cellsCellular senescence
Saturday, August 31
Cytotherapy
Advancing immunomodulatory functions in mesenchymal stem/stromal cells through targeting the GATA6-mediated pathway
Experiments in human cellsMechanisms
Saturday, August 10
Cancers
Insulin Resistance in Women Correlates with Chromatin Histone Lysine Acetylation, Inflammatory Signaling, and Accelerated Aging
Cross-sectional study of 245 peopleTNF signaling
Friday, July 22
Veterinary Immunology and Immunopathology
Effect of aging on monocyte phagocytic and inflammatory functions, and on the ex vivo inflammatory responses to lipopolysaccharide, in horses
Experiments in 7 horsesInflammation
Friday, January 21
Cellular and Molecular Life Sciences
WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion
Experiments in human cellsWnt/β-catenin signaling
Wednesday, November 17
Research Square
AP-1 complex activation is a conserved signature of immune system aging and a potential regulator of inflammaging in human and mice
Preprint: experiments in miceEpigenetic regulation of gene expression
Saturday, June 10
Frontiers in Genetics