HSD11B2

1. Glycyrrhetinic acid inhibits HSD11B2.

   “11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) inhibition by glycyrrhetinic acid.”

   Review

   Next-Generation Adaptogens: Molecular Mechanisms, Bioactive Compounds and Human Health Relevance of Selected Botanicals and Fungi

   International journal of molecular sciences·25 Sep 2026

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1. HSD11B2 increases dental pulp fibrosis in mice.

   “In vivo inhibition of the PDGF/P38/11β-HSD2 axis attenuates age-related pulp fibrosis.”

   Animalsduring agingdental pulp

   Age-associated niche remodeling drives dental pulp progenitor dysfunction and fibrosis

   Communications biology·7 Jul 2026

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1. PDGFB induces HSD11B2 in mice.

   “macrophage-derived PDGFB induces 11β-HSD2 via the P38 MAPK signaling.”

   Animalsvia P38 MAPK signalingdental pulp

   Age-associated niche remodeling drives dental pulp progenitor dysfunction and fibrosis

   Communications biology·7 Jul 2026

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