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FARNESYL-PRELAMINA

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab
  • Funder: National Heart, Lung, and Blood Institute
  • Animals1

Effects

1

Smooth muscle cells

no changein mice1

1 study

  1. FARNESYL-PRELAMINA has no effect on smooth muscle cells in mice.

    “In contrast, farnesyl-prelamin A in Zmpste24 -/- mice does not cause SMC loss-even at 21 weeks of age.”

    AnimalsZmpste24 -/- miceaorta

    The Accumulation of Progerin Underlies the Loss of Aortic Smooth Muscle Cells in Hutchinson-Gilford Progeria Syndrome

    bioRxiv : the preprint server for biology3 Nov 2024Preprint

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